Wednesday, May 22, 2024
engineered enzymes for better healthcare

· US Patent 5,798,234 (1998) Method for the Directed Modification of Enzymes, Modified Enzymes and Their Use

· Irish Patent Application No. S2005/0305 (2005) Amino Acid Dehydrogenase-Derived Biocatalysts

· P. Busca, F. Paradisi, E. Moynihan, A.R. Maguire & P.C. Engel. Enantioselective synthesis of non-natural amino acids using phenylalanine dehydrogenases modified by site-directed mutagenesis. Organic and Biological Chemistry (2004) 2, 2684-2691

· G. Cainelli, P.C. Engel, P. Galletti, D. Giacomini, A. Gualandi & F. Paradisi. Engineered phenylalanine dehydrogenase in organic solvents: homogeneous and biphasic enzymatic reactions. Org. Biomol. Chem. (2005) 3, 4316-4320  

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