Thursday, May 23, 2019
engineered enzymes for better healthcare

The range of amino acids currently amenable to these biocatalysts includes:

  • phenyl glycine, phenyl methyl glycine, homophenylalanine,
  • substituted phenylalanine derivatives (-CH3 , -OCH3, halogen etc.
  • heteroaromatic rings e.g. pyridine;
  • alicyclic rings e.g. cyclopentane, cyclohexane;
  • fused rings e.g. both variants of naphthyl alanine, tryptophan;
  • aliphatic chains with ethylenic and acetylenic bonds – permitting further derivatisation.

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